Kambo, Sapo or Acate are just a few of the names for a traditional “natural” medicine that is used as a remedy by various indigenous tribes of the Amazon. It consists of the secretion from the Kambo Frog. A South American nocturnal treefrog (lat. Phyllomedusa bicolor) that has no enemies due to this powerful secretion.

The potent effect is immense on the whole human organism and can be use to aid in healing for many ailments.  The local tribesmen traditionally use it for:

  • Healing and cleansing of the body
  • Physical strength and stamina
  • Spiritual and mental clarity
  • Luck and zest of life.

Each person who experiences this sacred medicine will have an individualized experience. A phone or in person consultation is needed before every session to ensure that the individuals personal needs and health is considered.

To inquire about a session or to discuss questions please email me at info.rhondadsmith@gmail.com to set up a phone or Skype call.

My personal relationship with Kambo has offered incredible healing. It has helped me find healing from seasonal allergies, weak immune system, depression, candida and codependency. This medication is not a psychedelic. In my opinion there is no greater detox. The healing impact of Kambo can’t really be measured. Each person has different results with the medicine. As a planet, we are in the trial stages of knowing the full potential of this medicine. We are in the forefront of uncovering its true potential.

I recently came across an article from a man who said Kambo brought incredible healing to his erectile disfunction. This medicine requires that you maintain a healthy lifestyle and diet for optimum benefit.


Kambo Soul Medicina sources medicine from sacred land from a known member of the Matses tribe. The extraction of this medicine is done with care and concern for each and every frog.

(The following information is sourced from several sites on the internet)

“Medical Research on Kambo

An Italian scientist, Vittorio Erspamer, of the University of Rome was the first to analyze Kambo in the lab.  Vittorio Erspamer was twice nominated for a nobel prize and was also responsible for first discovering the well known neurotransmitter Serotonin.   Erspamer concluded that Kambo contains a ‘fantastic chemical cocktail with potential medical applications, unequalled by any other amphibian’. His findings brought great attention to the area of peptides which have since become very important to the medical field.

Vittorio Erspamer was an Italian pharmacologist and chemist, known for the identification, synthesis and pharmacological studies of more than sixty new chemical compounds, most notably serotonin and octopamine. (Wikipedia)
The research activities of Erspamer spanned more than 60 years and resulted in the isolation, identification, synthesis and pharmacological study of more than sixty new chemical compounds. Among these compounds were polypeptides and biogenic amines, and also some alkaloids. Most of these compounds were isolated from animals, predominantly amphibians.

In the late fifties, his research shifted to peptides.  In the laboratories of the Institute of Medical Pharmacology, University of Rome, he isolated from amphibians and mollusks more than fifty new bioactive peptides. These became the subjects of numerous studies in other laboratories in Europe and North America.  In 1979, he focused on opioid peptides specific to Phyllomedusa tree frog from Central and South America.   These were used by the native Indians in initiation rites, to increase their prowess as “hunters” and make them feel “invincible”.   They applied secretions from the skin of these frogs that resulted in analgesic effects.

The peptides discovered by Erspamer {in Kambo} trigger a variety of beneficial chemical reactions in the human body.  Kambo has the ability, unlike many other natural and pharmaceutical substances, to cross the blood-brain barrier, enabling it to reach deep into the body and bring support to otherwise difficult to treat areas.  Human cells open up to the beneficial properties of Kambo unlike many substances that are filtered and eliminated by the body’s highly intelligent defense system. Thus far, researchers have discovered nine peptides, some of which are bio-active – meaning that they perform specific functions in the body.   These peptides perform hormone-like tasks while others provide support to vital cellular processes.  Some of these peptides have a potent effect on the gastrointestinal muscles, gastric and pancreatic secretions, blood circulation, and on the stimulation of the adrenal cortex and pituitary gland.   Many peptides have since been isolated from the Kambo secretion and have been synthesized.  As a testament to their medicinal properties, there are over 70 Kambo patents lodged, mainly in the USA.

Kambo also contains certain neuropeptides that are small, protein-like molecules used by the neurons to communicate with each other.  These neuronal signaling molecules are involved in a wide range of brain functions including:

  • analgesia
  • reward
  • food intake
  • metabolism
  • reproduction
  • social behaviors
  • learning
  • memory.

Ongoing research on peptides, Kambo’s main components, continues to evolve and find medical applications in the world of medicine and pharmacology.

The major peptides identified in the Kambo secretion include:

Phyllomedusin – strongly affects intestines, bowels and contributes to deep purging of toxins.

Phyllokinin and Phyllomedusin – both potent vessel dilators, increasing the permeability of the blood-brain barrier.

Caerulein and Sauvagine – cause a fall in blood pressure accompanied by tachycardia, stimulating the adrenal cortex and the pituitary gland and contributing to heightened sensory perception and increased stamina.  These peptides have a strong analgesic effect, enhance endurance, increase physical strength, and in general, enhance the capacity to manage physical pain and stress.  They possess medical uses as digestive aids, and have demonstrated analgesic effects for those with renal colic, pain due to peripheral vascular insufficiency and cancer.

Dermorphin and Deltorphin are potent opioid peptides 4000 times stronger than morphine and 40 times stronger than endogenic b-endorphines.

Adenoregulin, discovered in the 1990’s by John Daly’s team at the National Institute of Health in the USA.  The dermaseptins group, including Adenoregulin, are part of a family of broad spectrum antimicrobial peptides involved in the defense of the naked skin of frogs against microbial invasion. These are the first vertebrate peptides to show lethal effects against the filamentous fungi responsible for severe opportunistic infections accompanying immunodeficiency syndrome and the use of immunosuppressive agents.  Adenoregulin works in the human body through the adenosine receptors, a fundamental component in all human fuel cells.  These receptors offer a target for treating depression, stroke seizures and cognitive loss ailments such as Alzheimer’s disease. Scientific research on the various peptides of Kambo are opening up new perspectives on how the human brain works.   See article: http://journal.frontiersin.org/article/10.3389/fphar.2014.00105/full.

The bioactive peptides and neuropeptides present in Kambo cover a wide range of potential medical uses including:

  • depression
  • migraines
  • blood circulation problems
  • vascular insufficiency
  • organ diseases
  • skin and eyes issues
  • fertility problems
  • AID’s
  • hepatitis
  • cancer
  • brain diseases such as Alzheimer’s and Parkinson’s
 Other interesting properties include Kambo’s anti-inflammatory effects and its capacity to destroy various types of microbes and viruses.  Recent studies have shown that Kambo contains multiple antimicrobial peptides effective against drug-resistant strains of bacteria, fungi, protozoa, parasites and virus. This is exciting news for the development of new and more efficient therapies able to treat antibiotic-resistant strains of infectious diseases.

Several years of research conducted at the University of Paris have shown the peptide Dermaseptin B2 to be very effective at killing certain types of cancer cells.  Research at Queens University in Belfast recently won a prestigious award for their ground breaking work with cancer and Kambo. Here is a link to some of the research on the Dermaseptin B2:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447859/.

More on Dermasptin B2 at this link: https://www.researchgate.net/publication/231743136_Antitumor_and_Angiostatic_Activities_of_the_Antimicrobial_Peptide_Dermaseptin_B2.

For anyone wishing additional information, the peptide families present in Kambo includes:

  • bradykinins (phyllokinin)
  • tachykinins (phyllomedusin)
  • caerulein
  • sauvagine
  • tryptophyllins,
  • dermorphins,
  • deltorphins
  • bombesins
  • andenoregulin
 Additional resource material: http://iakp.org/research-links/4584763576.

Kambo is one of the strongest, anti-inflammatory, antibiotic, antimicrobial and anesthetic substances on the planet.  It is being studied for its effects on various types of cancer and for use in anti-biotic resistant strains of bacteria.  There is anecdotal evidence and regular use amongst the tribal women to assist overcoming infertility.” (information sourced from kamboalchemy.com)

Women must ensure that that they are not pregnant because Kambo will terminate the pregnancy.

Women who are nursing would need to get pump to discard the milk. The exact amount of time that the Kambo takes to fully leave the body can vary depending upon many factors. All precautions must be taken to ensure that babies and children do not ingest milk with Kambo in it. Children in the Matses tribe have been known to take the medication to help them step more into their courage. The medication hasn’t been known to harm them but it is not recommended by this practitioner to expose children through breast milk or any other means.

“A Kaxinawá tribe legend tells that the Indians of the village were very ill and the Shaman “Kampu” had done everything that was possible to cure them. All medicinal herbs known were used, but none helped his people’s agony. Kampu then entered the forest and under the effect of Ayahuasca, where he received the visit of the great God. He brought in His hands a frog, from which He took a white secretion, and was taught how to apply it. Returning to the tribe and following the guidelines that he had received. The Shaman Kampu was able to cure his tribe. After his death, the spirit of Kampu has started living in the frog and the Indians began to use its secretion to stay active and healthy.”- kambonaturista.com

Steps to prepare for your Kambo session:

Step 1: Do your research and plan a call before the session with your certified paractioner.

Step 2: Disclose all health conditions to your practitioner ahead of time. All medication must be stopped the day of the treatment. Some medications need to be stopped 5 days prior to treatment. Please refrain from smoking marijuana the day of the treatment.

Step 3: Fasting is required to ensure that the medicine works properly. A minimum of a 6 hour fast is required but a 12 hour fast is preferred.

Step 4: Only drink water on the day of treatment. Do not drink a lot of water, just enough to hydrate.

Step 5: Please bring a minimum of 2 liters of “room temperature” water with you to the session. Do not drink the water until instructed by the practitioner.

Step 6: Be clear on your intention for the session. This is an important part of the healing.

Step 7: Be open with your practitioner about how you are feeling. Open communication allows for a much deeper space of healing.

Step 8: Wear comfortable clothing that allows you to move with ease.

Step 9: This medicine is a gift and it is an honor to have the opportunity to bring this medicine to our communities. Be open to the process and the integration that comes with it.

Aho! Please reach out with your questions. The healing you desire is waiting.

info.rhondadsmith@gmail.com (Please type Kambo Session in the subject line)

Additional links and articles.

The Essential Guide to Kambo

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